10 Science-Backed Supplements for Promoting Gut Health

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Your gut plays an integral part in your overall health, from digestive function and energy levels to immune regulation and cognitive wellness. Therefore, supporting it to maintain overall well-being and avoid chronic illnesses is imperative.

Maintaining a healthy microbiome can aid with various conditions, including inflammatory bowel diseases (IBDs), IBS, Crohn’s disease, and digestive issues such as leaky gut. Furthermore, maintaining an intact gut lining may prevent further issues that lead to chronic health conditions like leaky gut.

Sometimes our regular diet may not be sufficient to improve gut bacteria. As such, you can consult a doctor and take supplements to support a healthy gut. There are different types of supplements available in the market for gut health. 

So, in this article, we are going to discuss the best science-backed supplements for promoting gut health. 

Gut Health Supplements

Gut health supplements are dietary supplements designed to support and strengthen the GI (GI) tract in various ways, from helping balance bacteria within your gut to decreasing inflammation.

Often top choices for gut health supplements combine probiotic strains that support good bacteria to remove any unwanted toxins from your digestive tract, offering relief from symptoms like bloating and irregular digestion such as Irritable Bowel Syndrome or constipation.

Another best natural supplement to improve gut health is fiber. Eating more fiber can be an easy way to support gut health, and selecting prebiotic fibers will feed the good bacteria in your digestive tract and support bowel movement.

10 Best Science-Backed Supplements for Gut Health

To maintain your gut ecosystem in harmony, you must consume foods and supplements that promote the diversity of microbes while providing essential nutrients to bacteria. Here are the best supplements  to promote gut health. 


Probiotics are live microorganisms that work to restore balance by decreasing harmful bacteria levels and supporting immune function. They also improve digestion and may contribute to overall wellness. Probiotics have another advantage in that they may help alleviate symptoms associated with the leaky gut syndrome – an intestinal condition in which cells lining the small intestine become loose and permeable to toxins and bacteria entering through. Probiotics have also proven useful in combatting inflammatory skin conditions like acne, psoriasis, and eczema.


L-glutamine is one of the key supplements to support gut health. Studies have demonstrated its beneficial properties by helping maintain the integrity of gut linings, increasing tight junction proteins, and improving immune response. The optimal dosage for glutamine may depend on your needs and condition; however, we believe 5 to 10 grams is an optimal serving size when feeding and nurturing your gut.

Slippery Elm

Slippery elm is an extremely beneficial digestive herb you can find in numerous supplements and herbal teas. It provides an abundance of mucilage – an adhesive substance that aids regularity – which has numerous health benefits for our bowels. People have also used slippery elm to treat psoriasis, an inflammatory skin condition. It can be consumed as a powder that can be mixed with 250ml of water and consumed either once or twice daily, depending on what it’s being used for.

Licorice Root

Licorice root (Glycyrrhiza glabra) has long been recognized for its medicinal properties. You can use it as a way to treat digestive ailments such as heartburn, acid reflux, and indigestion. This effect is due to glycyrrhizin acid present in its roots, which helps heal damaged stomach linings while suppressing H. pylori growth that could otherwise lead to stomach ulcers or gastritis.


Inulin is prebiotic that promotes healthy bacteria to thrive in your gut, making an impactful contribution to overall wellness. It may help relieve constipation by absorbing water in the bowel and producing a gel-like substance to soften stool. You can find insulin in fruits and vegetables as well as other foods like oats and soybeans and comes in powdered forms to add to smoothies or shakes every day.

Collagen Protein Powder

Collagen protein powder is an easy and convenient way to increase collagen intake, supporting a healthy immune system and gut lining while simultaneously stimulating an anti-inflammation response. Finding a collagen supplement that’s easily digestible, bioavailable, and free from added sugars or additives is key to getting maximum results from taking supplements.

Moringa Leaf Powder

Moringa leaf powder is an evidence-based supplement designed to support gut health. This plant’s leaves contain numerous essential vitamins and minerals essential for digestive health and weight loss. It also contains anti-inflammatory, antioxidant, stress-fighting, and detoxifying agents that support these objectives.


Psyllium husk is an innovative dietary fiber that helps with digestive issues like constipation and diarrhea. People living with IBS often take psyllium to alleviate symptoms like abdominal pain and bloating. You can purchase Psyllium  in both whole husks and powdered forms from health food stores and online vendors. Psyllium husk powder should then be mixed with a liquid such as water before being taken orally.


Peppermint can be an invaluable aid for soothing spasms in the digestive tract and may help alleviate symptoms of IBS. Furthermore, its soothing anti-inflammatory properties relieve inflammation while simultaneously relaxing stomach muscles. Oil may be taken orally as capsules or mixed with water for consumption.


Artichokes are an excellent source of antioxidants and may help improve digestive health. Furthermore, artichokes contain prebiotics and probiotics, which support healthy intestinal bacteria growth. Studies indicate that artichoke extract may help soothe symptoms of indigestion, such as stomach pain, cramping, and diarrhea. 


Gut health is an integral component of overall well-being. Yet many individuals struggle with digestive symptoms or imbalances that impair their quality of life. Natural supplements significantly boost gut health and optimize microbiome function, though not all supplements may be appropriate for everyone. So, be sure to speak to your healthcare provider prior to changing the dosage or adding new supplements.

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