What are the 3 Main Causes of Depression?

Main Causes of Depression

Depression can occur in anyone and is incredibly common. In fact around 20% of people will have depression at some point in their life, though this figure may be much higher. Women tend to be diagnosed with depression more than men, but this may simply reflect that women are more likely to seek help from their doctors than men.

Depression symptoms vary between individuals but generally the overriding symptom is that of feeling low for an extended period of time. This is different to just feeling sad. The symptoms of depression can have a considerable impact on day-to-day life for some individuals. It can impact their relationships, and can even prevent them from working, getting out of bed and performing basic self care activities.

Here are some of the symptoms you may experience if you have depression:

  • Feeling irritable
  • No longer getting pleasure from activities that you once enjoyed
  • Having trouble sleeping whether, that is too much or too little
  • Feeling tired and fatigued throughout the day
  • Increased or reduced appetite
  • Feelings of anxiety and restlessness
  • Issues remembering and concentrating 
  • Feelings of worthlessness
  • Suicidal thoughts 
  • Feeling hopeless 
  • Feeling bad about yourself
  • Low libido

These are just a few examples of the symptoms of depression and they can range greatly in severity between individuals. You may experience some (or all) of these very lightly whereas others may feel crippled by them.

If you are unsure if you have depression and would like to get a better idea of your mental health,  you can take the PHQ-9 screening questionnaire that your GP would use to get an idea of whether you are depressed or not. 

The Main Causes of Depression

Why do people get depressed? The brain is a perpetual mystery and as such the main causes of depression are not fully understood. However, we do know what can trigger, exacerbate, and put us at a higher risk of depression. 

Physical Conditions

Physical pain has been shown to have a link to depression. This means that for people with chronic pain and illnesses such as fibromyalgia, which causes widespread pain in the body, they may be more at risk of depression. This can also be the case with other physical health problems like Alzheimer’s, rheumatoid arthritis, psoriasis as they influence your lifestyle or how you live your life.

Life Events

It will likely come as no shock that the busy lives we lead can have a detrimental impact on our mental health. Sometimes life throws us curve balls that can not only be really challenging, but can trigger depression. Examples include being made redundant from a job, grief from losing someone you love, a relationship breakdown, trauma (whether this happened as a child or adult), and being bullied. Any life event can trigger depression – not just negative ones – and so can a build up of smaller events. 

Family Medical History

Although there is currently no gene for depression, there are clear correlations showing that if your parents or close relations have had depression, this can increase your risk of depression. However, the good news is that this doesn’t guarantee that you will develop it. 

The truth is that there are many factors that can make us more vulnerable to depression. These include persistent sleep problems, drugs and alcohol use. Even certain medications have depression as a side effect.

Getting Help for Depression

The good news is that many people with depression are able to recover and lead happy and fulfilling lives with the help of treatment.

Some of the most common treatments for depression include Cognitive Behavioural Therapy (CBT) and antidepressants. You may or may not find these effective –  in some cases, people find that CBT and antidepressants are not helpful and that their symptoms persist. In these cases, a non-invasive, drug-free treatment for depression, called repetitive Transcranial Magnetic Stimulation (rTMS) can be used. rTMS treatment for depression is only available in very limited locations on the NHS and most people will need to seek this treatment from a private clinic. 

rTMS works by gently stimulating the part of the brain that regulates mood. It is a very effective treatment for depression and has been used for years in the US before coming to the UK.

But how do you know when to seek help for depression? If you have been feeling low for more than two weeks or if any of the above symptoms are affecting your life and making day-to-day life difficult, it’s time to seek help from your GP or from a private clinic. 

If you have a friend who you think may be suffering with depression, it can be helpful to make it clear you are there for them if they want to talk, and to suggest that they seek guidance from a professional. Sometimes, just knowing that a friend or family member is there to support you can make a whole world of difference.


Subscribe to Our Newsletter

Related Articles

Top Trending

ControlNet composition guide
ControlNet and Composition Control in AI Images: A Practical Guide
On This Day June 27
On This Day June 27: History, Famous Birthdays, Deaths & Global Events
AI-Powered Playtesting
Top 10 Gaming SMEs and Startups Specializing in AI-Powered Playtesting in the United States
habits reduce stress
7 Habits That Reduce Stress Long Term and Feel Calmer Daily
Newsletter Strategies for Publishers
7 Newsletter Strategies for Publishers That Turn Readers Into Regulars

Fintech & Finance

Term Insurance Premiums with Online Calculators
Understanding Term Insurance Premiums with Online Calculators
Loan for Professionals vs Lawyer Loan
Loan for Professionals vs Lawyer Loan: Which Financing Option is Right for Legal Professionals?
How a Gold Rate Calculator Helps You Value Gold Jewellery Before Pledging
How a Gold Rate Calculator Helps You Value Gold Jewellery Before Pledging 
Best Corporate Bonds
Credit Ratings Drive Everything in Corporate Bonds — How to Compare the Best Corporate Bonds Side by Side 
Understanding SIP Investing in Mutual Funds for New Investors
Understanding SIP Investing in Mutual Funds for New Investors

Sustainability & Living

climate investment decisions
8 Climate Investment Decisions for Climate-Conscious People
sustainable insulation materials
Sustainable Insulation Materials Explained: Best Eco Options for Greener Homes
French sustainable software engineering
6 French Startups and SMEs Shaping Sustainable Software Engineering
climate action steps
31 Climate Action Steps Individuals Can Take Without Feeling Powerless
Scottish wave and tidal energy companies
10 Scottish Startups, Scaleups, and SMEs Shaping the Wave and Tidal Energy Sector

GAMING

AI-Powered Playtesting
Top 10 Gaming SMEs and Startups Specializing in AI-Powered Playtesting in the United States
Best Gaming Communities
25 Gaming Communities and Platforms You Must Join Today
Best Speedrunning Communities
7 Best Speedrunning Communities for Runners, Fans, and Record Hunters
Best esports communities guide by general hubs game communities forums local scenes and competition platforms
The 11 Best Esports Communities Worth Joining for Fans and Players
The Architecture of Play Engineering the Next Era of Digital Entertainment Ecosystems
The Architecture of Play: Engineering the Next Era of Digital Entertainment Ecosystems

Business & Marketing

Markup Strategy That Lets Agencies Stay Competitive Without Racing
The Markup Strategy That Lets Agencies Stay Competitive Without Racing to the Bottom
Content Curation Strategies
9 Practical and Effective Content Curation Strategies for Niches
Venture Capital Process
Venture Capital Process Walkthrough: What Founders Should Expect Before Raising
Convertible Notes vs SAFEs
Convertible Notes vs SAFEs Compared: The Founder’s Practical Guide
AI Creative Workflows
23 AI Creative Workflows for Different Industries

Technology & AI

ControlNet composition guide
ControlNet and Composition Control in AI Images: A Practical Guide
AI Image Upscaling Guide
Understanding AI Image Resolution and Upscaling Guide for Better Images
partner marketing SaaS
Partner Marketing for SaaS: How to Build Partnerships That Actually Drive Growth
ARK Augmented Reality
ARK Augmented Reality: Complete 2026 Guide to Microsoft's AI Framework and Where the Technology Stands
bootstrap vs funded startup
Bootstrap vs Funded Startup Paths Compared: Which Growth Route Fits Your Business?

Fitness & Wellness

habits reduce stress
7 Habits That Reduce Stress Long Term and Feel Calmer Daily
habits better focus
11 Habits for Better Focus That Actually Work
meditation aids tools
11 Meditation Aids and Tools That Support Daily Calm
sleep products that help
9 Sleep Products That Actually Help
home recovery products
7 Home Recovery Products Worth It for Sore Muscles, Mobility, and Post-Workout Relief