Top 11 Medical Technology Startups in Singapore for 2025

Singapore has firmly established itself as a global hub for innovation, especially in the field of medical technology. Its strong government support, robust healthcare infrastructure, and strategic location have attracted numerous groundbreaking startups. 

These companies are revolutionizing the healthcare landscape, offering solutions ranging from AI-powered diagnostics to advanced surgical tools. In this article, we’ll explore the top 11 medical technology startups in Singapore to watch in 2025. 

Each company is paving the way for a healthier future, blending cutting-edge technology with a patient-centered approach.

At a Glance: Top 11 Medical Technology Startups in Singapore

Here is a quick overview of the startups featured in this article:

1. Holmusk

Holmusk specializes in digital health and analytics, focusing on mental health and chronic disease management. 

The company uses big data and machine learning to turn complex datasets into actionable insights for healthcare providers. 

Its flagship platform, NeuroBlu, integrates clinical data with behavioral patterns to enhance the accuracy of mental health treatment plans. 

Holmusk’s solutions enable clinicians to make data-driven decisions, ultimately improving patient outcomes. 

Their commitment to mental health innovation is transforming how these conditions are treated globally, addressing gaps in data availability and analysis.

Key Contributions:

• Data-Driven Insights: Revolutionizing mental health treatments through advanced analytics.
• Global Impact: Expanding partnerships with healthcare providers worldwide.

2. (Vivance) AWAK Technologies

AWAK Technologies has redefined kidney care with its portable peritoneal dialysis system. 

The company’s innovative device reduces the burden on patients who rely on traditional dialysis methods by offering a compact and user-friendly solution for at-home use. 

Its proprietary sorbent technology minimizes fluid requirements, reducing treatment time and costs. 

As kidney disease becomes increasingly prevalent, AWAK’s patient-centric approach offers significant improvements in quality of life.

Their advancements align with Singapore’s vision to lead in med-tech innovation.

Key Contributions:

• Accessibility: Providing a portable dialysis solution for easier patient management.
• Sustainability: Reducing hospital visits and healthcare costs.

3. HistoIndex

HistoIndex is a pioneer in providing AI-based imaging solutions for fibrosis diagnosis and treatment. 

Their proprietary Genesis® Imaging System uses quantitative imaging to analyze liver and other tissue samples, providing clinicians with precise and reproducible data.

This approach enables early detection and improved management of chronic diseases such as non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH).

 HistoIndex’s innovations are setting new standards in histopathology.

Key Contributions:

• AI-Driven Diagnostics: Revolutionizing fibrosis detection with cutting-edge imaging.
• Global Impact: Providing tools to improve outcomes for chronic liver conditions.

4. Aevice Health

Aevice Health creates smart respiratory monitoring devices for chronic respiratory conditions like asthma and COPD. Their wearable device, AeviceMD, tracks respiratory patterns and provides real-time alerts for anomalies. 

By leveraging AI, Aevice enables early detection of respiratory exacerbations, ensuring timely intervention. 

With air pollution and respiratory illnesses on the rise, Aevice’s solutions are a critical addition to healthcare systems worldwide. 

The company’s focus on patient comfort and accessibility makes their technology stand out.

Key Contributions:

• AI-Powered Alerts: Helping prevent respiratory emergencies.
• Patient-Friendly Design: Creating discreet and comfortable wearables.

5. Privi Medical

Privi Medical addresses gastrointestinal disorders with non-invasive medical devices. Their flagship product provides a pain-free solution for hemorrhoid treatment, reducing the need for surgical procedures. 

By focusing on common yet under-treated conditions, Privi Medical has positioned itself as an industry leader in gastrointestinal care. 

The company’s commitment to innovation ensures that patients receive effective treatments without the complications of traditional methods.

Key Contributions:

• Ease of Use: Simplifying treatment for GI conditions.
• Affordable Solutions: Making advanced care accessible to all.

6. MiRXES

MiRXES specializes in RNA-powered precision diagnostics. The company has developed innovative molecular diagnostic tests, including GASTROClear, the world’s first blood-based microRNA test for early gastric cancer detection. 

MiRXES focuses on creating reliable, minimally invasive tools for disease screening and monitoring, with applications extending to cardiovascular and infectious diseases. 

Their technology combines cutting-edge molecular science with scalable platforms, enabling high-throughput diagnostic solutions. 

MiRXES is committed to empowering clinicians with better tools to improve patient outcomes through early intervention.

Key Contributions:

• Early Disease Detection: Revolutionizing cancer and disease diagnostics with RNA-based tests.
• Scalability: Developing diagnostic solutions that are accessible and efficient.

7. Us2.ai 

Us2.ai specializes in automating the analysis of echocardiograms using AI to reduce the time and complexity of cardiovascular diagnostics. 

Their platform automates measurements, interpretations, and reporting of heart scans, significantly enhancing clinical efficiency. 

Us2.ai’s technology integrates seamlessly into existing workflows, making it a valuable tool for hospitals and clinics worldwide. 

The company is focused on democratizing access to advanced heart health diagnostics.

Key Contributions:

• Time Efficiency: Reducing echocardiogram analysis time from hours to minutes.
• Scalability: Making advanced diagnostics accessible globally.

8. Biofourmis

Biofourmis is a pioneer in digital therapeutics and predictive analytics for personalized healthcare. The company’s Biovitals® platform leverages wearable sensors and AI to monitor patient health remotely. 

It provides insights into physiological changes, allowing early detection of potential health issues. Biofourmis specializes in managing chronic conditions, such as heart failure and oncology-related complications. 

By combining digital tools with therapeutic interventions, the company enables clinicians to deliver proactive and tailored care, reducing hospitalizations and improving patient outcomes.

Key Contributions:

• Digital Therapeutics: Advancing healthcare with AI-driven patient management solutions.
• Remote Monitoring: Empowering patients and clinicians with continuous health tracking

9. EndoMaster

EndoMaster is revolutionizing minimally invasive surgeries with robotic endoscopy technology. The company’s EndoMaster EASE platform enables surgeons to perform precise, incision-free surgeries using robotic-assisted endoscopes. 

This innovation is particularly impactful in gastrointestinal treatments, offering a less invasive alternative to traditional procedures. 

By reducing patient recovery time and lowering surgical risks, EndoMaster is transforming the landscape of surgical care globally.

Key Contributions:

• Incision-Free Surgery: Enabling minimally invasive treatments with robotic endoscopy.
• Improved Outcomes: Enhancing patient recovery and reducing healthcare costs.

10. Stratificare 

Stratificare develops predictive diagnostics for infectious diseases, focusing on personalized treatment strategies.

Their flagship product, StratifiDx, predicts the severity of dengue fever, helping clinicians prioritize resources and provide timely interventions.

The company combines biomarker-based diagnostics with AI to tackle infectious disease challenges in Southeast Asia and beyond. 

Stratificare’s solutions are pivotal in improving outcomes for resource-constrained healthcare systems.

Key Contributions:

• Disease Severity Prediction: Helping clinicians manage infectious diseases efficiently.
• Regional Focus: Addressing healthcare challenges in Southeast Asia. 

11. Oncoshot

Oncoshot is an oncology-focused platform that connects patients, clinicians, and clinical trial researchers. By using AI and big data, Oncoshot identifies suitable clinical trials for cancer patients, accelerating the matching process and increasing access to innovative treatments. The platform also helps researchers identify eligible participants faster, streamlining the trial process. Oncoshot’s mission is to advance cancer care through collaboration and data-driven insights.

Key Contributions:

• Trial Matching: Facilitating access to cutting-edge cancer treatments.
• Collaborative Innovation: Connecting patients and researchers to improve outcomes.

Takeaway

Singapore’s medical technology startups are leading a healthcare revolution, offering innovative solutions to pressing health challenges. 

From AI-driven diagnostics to groundbreaking wearable devices, these companies are shaping the future of medicine. 

With robust support and a commitment to excellence, these startups are not just transforming healthcare in Singapore but inspiring the global med-tech landscape.